Cellular energyEnergy
Your cells use NAD+ in reactions that release energy from nutrients.
Licensed clinician review Licensed U.S. pharmacy
Why all the talk about NAD+?
A coenzyme every cell uses to turn food into energy, and researchers are studying how it changes with age.
Plain, discreet packaging. Tracking sent to your email.
Starting at $1591-month plan, shipping included
- 100% online. Intake from your phone, no waiting room.
- Consultation included. A licensed clinician reviews every order.
- One price, paid once. No membership, no auto-renewal.
- Free shipping. On 3- and 6-month plans.
- No membership fee
- Paid upfront, no auto-renewal
- Refund if a clinician does not prescribe
AS REVIEWED IN · PARTNER REVIEW
Prescription required. A licensed clinician decides whether treatment is appropriate for you; availability varies by state. Compounded medications are not FDA-approved; FDA does not review them for safety, effectiveness, or quality before marketing.
Licensed clinician review on every order Consultation included Prepared by a licensed U.S. pharmacy Full total shown before checkout No membership fee Refund if a clinician does not prescribe
Why everyone keeps talking about NAD+
One molecule. Six big questions.
Cell energy
NAD+ helps turn the food you eat into the energy your cells run on. That is how cells work. It is not a promise about how energetic you will feel.
The brain
Your brain is one of the hungriest organs you have. Researchers are studying NAD+ in brain cells. Whether an NAD+ injection changes focus in people has not been established.
Aging
One study of human skin samples found lower NAD+ levels at older ages. Whether raising NAD+ changes anything is the question science is working on.
DNA repair
Some of the enzymes that repair DNA use up NAD+ as they work. That is basic biology, not a promised result.
Skin cells
Skin cells use NAD+ like every other cell. The study linked below measured NAD+ in skin samples. It did not test any treatment.
Muscle
Muscle cells use NAD+ when they turn fuel into energy during exercise. That does not show that an injection changes recovery.
These describe biology and research topics. They are not measured treatment results or a promise of benefit. Source for the aging and skin lines: Massudi et al., 2012, a study of human skin samples.
- No membership fee
- Paid upfront, no auto-renewal
- Refund if a clinician does not prescribe
The offer
More months. More savings.
- $0 consultationLicensed clinician review, included with every plan
- Free shippingOn 3- and 6-month plans. Most orders ship within 2 to 3 business days of approval
- Save up to $155On the 6-month plan, against six one-month plans at $159 each, shipping included
Start here
One-month plan
$159total today
$149 medication + $10 shipping
Try one monthSame medication, same clinician review. Order again when you are ready.
- $10 shipping
- Consultation included
- Paid once, no auto-renewal
Works out to $159 a month for medication, consultation and shipping.
Save $58
Three-month plan
$419total today
3 one-month plans would cost $477
You save $58against 3 one-month plans, and shipping is free
- $28 off medication
- Free shipping, instead of $10 a month
- Consultation included
- Paid once, no auto-renewal
Works out to $139.67 a month for medication, consultation and shipping.
Save $155Biggest saving
Six-month plan
$799total today
6 one-month plans would cost $954
You save $155against 6 one-month plans, and shipping is free
- $95 off medication
- Free shipping, instead of $10 a month
- Consultation included
- Paid once, no auto-renewal
Works out to $133.17 a month for medication, consultation and shipping.
Tap a plan to see exactly what you pay and what you save.
- No membership fee
- Paid upfront, no auto-renewal
- Refund if a clinician does not prescribe
Prescription required. Compounded medications are not FDA-approved. Any labs your clinician requires are priced separately. Payment does not guarantee a prescription. Savings compare each plan with the same number of one-month plans at $159 each ($149 medication plus $10 shipping).
What you get
Medication, consultation and shipping in one total.
From $159 for one month. You see the full total before you pay. Any labs your clinician requires are priced separately.
Most orders ship within 2 to 3 business days of clinician approval, with tracking sent to your email.
Get started
Your one-month total
- NAD+ medication
- $149
- Online consultation
- $0
- Shipping
- $10
- Total today
- $159
3- and 6-month plans ship free.
- 100% online, no waiting room
- Licensed clinician review included
- No insurance needed
- No membership fee
- One price, paid once
- Free shipping on 3- and 6-month plans
- Refund if a clinician does not prescribe
- Plain, discreet packaging
Not all NAD+ is sold the same way.
NAD+ is sold three very different ways online. Only one of the three requires a prescription and a clinician’s review.
Swipe sideways to compare all three. The product images are illustrations. They do not show any specific brand, and your medication may look different.
| All three are illustrations. They do not show any specific brand, and your medication may look different. | |||
| What to check | Prescription NAD+ through YESCLINICPrescription injection | Vials sold online without a prescriptionNo clinician involved | Oral NAD+ supplementsSold as a supplement |
|---|---|---|---|
| Prescribed for you | Only if a licensed clinician approves, after review | No prescription involved | No. Sold as a dietary supplement |
| Who prepares it | A licensed U.S. pharmacy, for you by name | Varies by seller. Not a pharmacy filling a prescription | A supplement manufacturer |
| Clinician review | A clinician reviews your health history | None included | None included |
| How it is taken | Injection, with instructions | Not sold with instructions for human use | By mouth |
| Price | From $159 for one month, consultation and shipping included | Varies by seller | Varies by brand |
| FDA-approved | No. Compounded medications are not FDA-approved | No | No. Supplements are not FDA-approved drugs |
An injection and an oral supplement are different products with different evidence. This table compares how each is sold, not how well it works.
The full science: what NAD+ does inside your cellsRead more
01 / GET TO KNOW NAD+
What NAD+ does inside your cells.
NAD+ stands for nicotinamide adenine dinucleotide. It is a coenzyme: a molecule that helps enzymes do their work. Your cells use it in reactions that turn nutrients into usable energy. This is its role in the body, not a promise about what an injection will do for you.
Why the interest in aging?
Researchers study how NAD+ metabolism changes with age. That makes it an interesting area of research, not proof that NAD+ injections reverse aging or improve how you feel.
Your next chapter is personal.
For women exploring wellness as they age, the useful question is: what fits my health history and goals? Being older does not automatically mean you need NAD+ or a combination of treatments.
Read the human-tissue researchA CLOSER LOOK · TAP A POINT
A coenzyme, not a peptide
NAD+ is a molecule that helps many of your enzymes do their work. Every cell in your body uses it.
Cellular reactions Energy metabolism A clinical question
Simplified explanation of biology. Not a prediction of treatment results. The vial shown is an illustration, and your medication may look different.
Get to know NAD+ before you decideRead more
Get to know NAD+ before you decide.
NAD+ is part of how your cells make energy. Understand its role, explore the evidence, and bring your goals to a licensed clinician.
Explore plansCellular energy
Evidence by routeRoute
An injection, an IV infusion and an oral supplement are different interventions with different evidence.
The years aheadAging
Understand what longevity research can and cannot tell us today.
These explain biology and topics for discussion. They are not measured treatment results or a promise of benefit.
For people who ask good questions
Wanting to age well is not vanity.
At some point the wellness noise gets loud. Everyone has a stack, a protocol, a podcast clip.
You can be curious about NAD+ without buying the hype. You can also have a licensed clinician review whether it makes sense for you, with your health history in front of them. That is what this page is for.
Explore your goals
THE QUESTION BEHIND ENERGY
What is behind the energy conversation?
NAD+ participates in energy metabolism. Whether a specific treatment improves how energized you feel is a separate clinical question.
Look at the evidenceResearch & treatment differencesRead more
03 / MAKE THE COMPARISON COUNT
The details make
the difference.
The same headline can describe very different products. Understand exactly what you are comparing.
NAD+ injection
A prescribed injection is a different route from an oral precursor. The formulation, instructions, and suitability need to be assessed together.
NR / NMN supplements
Precursors are ingredients the body can use to make NAD+. Their studies do not establish the effects of an NAD+ injection.
Ask about the ingredient, route, evidence, and practical fit. A different delivery method does not automatically mean a better outcome.
04 / THE EVIDENCE, OPENLY
Know what’s behind
the headline.
Good decisions need context. Here is one relevant study, and what it can and cannot tell us.
RESEARCH NOTE01HUMAN STUDY
ROUTE MATTERS
ROUTE MATTERS
Grant et al., 2019 · Exploratory IV study
The published IV pilot explored metabolism. It was not a trial demonstrating improved daily energy or lifespan.
A small pilot study examined metabolites during a six-hour intravenous NAD+ infusion. It helps researchers understand what happens to infused NAD+; it does not establish lasting improvements in energy, cognition, or aging, and it did not test the injection offered through YESCLINIC.
Read the original studyYOUR NAD+ JOURNEY
Your next chapter, one check-in at a time.
Explore useful check-in points. Your clinician sets your actual schedule; these are care conversations, not a timeline of promised results.
Start with a plan you understand.
If treatment is prescribed, confirm the instructions, storage and how to reach your care team. Your clinician will explain the plan before you begin.
01 / 05
Care, made clear: the full care pathRead more
WHAT TO EXPECT WITH YESCLINIC
Care, made clear.
01
Explore the guide and choose the plan you want a clinician to review.
View plans
Prescription required. Consultation included. $10 shipping for one month; free for three or six months.
NAD+ care, without the waiting room.
Licensed clinician review, from your phone. No insurance needed.
- TodayPick your plan and pay securelyYou see the full total before you pay. One payment, nothing renews, no membership.
- Online, from your phoneComplete a short health intakeYour health history, the medications you take now, and anything a clinician should know.
- Clinician reviewA licensed clinician reviews your historyThey decide whether this treatment is appropriate for you. If they decide it is not, you are refunded in full.
- If prescribedA licensed U.S. pharmacy prepares your orderCompounded for you by name and labelled with instructions for use.
- Plain, discreet packagingDelivered to your door with trackingNothing on the outside says what is inside. Tracking is emailed to you.
If a clinician decides treatment is not right for you, your payment is refunded. Read the refund policy
Most orders ship within 2 to 3 business days of clinician approval, with tracking sent to your email. Payment does not guarantee a prescription.
Ready when you are.
Choose a plan and complete your intake online.
- No membership fee
- Paid upfront, no auto-renewal
- Refund if a clinician does not prescribe
THE CULTURE. THE SCIENCE. THE CONTEXT.
Behind the
NAD+ conversation.
Heard about NAD+ on a podcast? Here is the science behind the conversation, and what is still uncertain.
Independent educational coverage. These guests and podcasts do not endorse YESCLINIC or its products. Discussion of a molecule is not proof of treatment benefits.
David Sinclair, PhD · DEC 27, 2021
Aging researcher · Huberman Lab
The biology behind the conversation.
NAD, sirtuins, and aging biology. Understanding a mechanism does not establish the benefits of a particular injection.
Read the sourcePeter Attia, MD · JUL 29, 2024
Physician and podcast guest · Huberman Lab
A closer look at the evidence.
NAD, NR, NMN, and the evidence behind longevity claims. Different ingredients and delivery routes are not interchangeable.
Read the sourceVideos load from YouTube only when you choose an episode. Loading a video connects to YouTube and is subject to its privacy practices. Learn more ↗
YOUR QUESTIONS. YOUR NEXT CHAPTER.YESCLINIC / NAD+
Ready to choose your plan?
Three plans, with consultation included. See your full total, including shipping, before checkout.
$0Consultation$10 / freeShipping by plan
Consultation included. Shipping is $10 for one month and free for three or six months. Any required labs are priced separately.
Prescription required. A licensed clinician decides whether treatment is appropriate for you; availability varies by state. Compounded medications are not FDA-approved; FDA does not review them for safety, effectiveness, or quality before marketing.
We have got you.
You have questions. Here are straight answers.
The names here are illustrative. These are example questions, not messages from real patients.
Michelle asks,I keep hearing about NAD+. What is it?
NAD+ is short for nicotinamide adenine dinucleotide. It is a coenzyme found in your cells and involved in energy metabolism. It is not a peptide, and its normal role in the body does not prove that an injection will produce a particular benefit.
Sarah asks,How much will I pay today?
The one-month plan is $159 total: $149 for the medication and $10 shipping. The three-month plan is $419 with free shipping, and the six-month plan is $799 with free shipping. Consultation is included. Any required labs are priced separately.
Diana asks,Will I be billed every month?
No. The one-, three- and six-month plans are each paid once, upfront. The plan length is shown before checkout.
Karen asks,What happens after I choose a plan?
You review the total, pay securely and complete a short medical intake. A licensed clinician then reviews your information and decides whether treatment is appropriate. Payment does not guarantee a prescription.
Jasmine asks,What if the clinician does not approve treatment?
If a clinician decides treatment is not right for you, your payment is refunded.
A common question,Will I feel different right away?
Nobody can responsibly promise when, or whether, you will notice a change. Responses vary from person to person. Follow the plan prescribed for you and contact YESCLINIC support with questions.
A common question,Will I feel more energetic in the first week?
There is no reliable universal first-week response. Energy has many influences, including sleep, nutrition, medications, and medical conditions. Persistent fatigue deserves an assessment rather than a presumed NAD+ deficiency.
A common question,Is NAD+ an anti-aging treatment?
The biology is of research interest. That does not establish that an injectable NAD+ program reverses aging or extends life in humans.
A common question,Is an injection the same as an NAD+ supplement?
No. Some supplements contain precursors that the body can use to make NAD+. An injected coenzyme is a different product and route.
A common question,What should I ask a clinician?
Ask what problem the treatment is intended to address, what evidence applies to the exact route, what alternatives exist, and how benefits and adverse effects would be assessed.
Ready to review your NAD+ options?
Compare all three plan totals, then choose the one you want a licensed clinician to review.
- No membership fee
- Paid upfront, no auto-renewal
- Refund if a clinician does not prescribe
IMPORTANT SAFETY INFORMATION
The FDA has received reports of severe chills, shaking, vomiting, and fatigue after injectable NAD+ products. Sterile preparation and appropriate ingredients matter. These reports do not establish that a particular YESCLINIC product was involved.
Compounded medications are not FDA-approved. FDA does not review their safety, effectiveness, or quality before marketing. This information is educational and does not replace a clinician’s assessment.
Read FDA informationKEEP EXPLORING